For research purposes only. This comparison describes the chemical identity and research context of Ipamorelin and CJC-1295 (without DAC). It is not medical advice, does not rank the compounds for any purpose, and does not describe any effect, dose, or use in humans or animals.
Ipamorelin vs CJC-1295 (without DAC) at a glance
| Attribute | Ipamorelin | CJC-1295 (without DAC) |
| Class | Synthetic pentapeptide (GHS) | Modified GRF (1-29) analogue |
| Length | 5 aa | 29 aa |
| Approx. molecular weight | ~711.9 g/mol | ~3368.7 g/mol |
| Receptor / target (research) | Ghrelin / GHS receptor | GHRH receptor |
| CAS number | 170851-70-4 | 863288-34-0 |
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide (five amino acids) with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2. In research literature it is described as a selective ghrelin / growth-hormone-secretagogue receptor ligand. It is supplied as a lyophilised powder for laboratory research.
Read more in our Ipamorelin research guide, or view the Ipamorelin product page.
What is CJC-1295 (without DAC)?
CJC-1295 without DAC (also known as Modified GRF 1-29 / Mod GRF 1-29) is a synthetic 29-amino-acid analogue of growth hormone-releasing hormone (GHRH), with amino-acid substitutions that improve stability relative to the native sequence. It is supplied as a lyophilised powder for research.
Read more in our CJC-1295 (without DAC) research guide, or view the CJC-1295 (without DAC) product page.
Key differences
As with the ipamorelin-versus-sermorelin comparison, the key difference is receptor class. CJC-1295 (without DAC / Modified GRF 1-29) is a 29-amino-acid GHRH-receptor analogue; ipamorelin is a 5-amino-acid ghrelin / GHS-receptor ligand. CJC-1295 differs from plain sermorelin by carrying stabilising amino-acid substitutions that improve enzymatic resistance, but it remains within the GHRH-receptor family.
How researchers distinguish Ipamorelin and CJC-1295 (without DAC)
In research the two represent different receptor families — GHRH receptor (CJC-1295) and ghrelin / GHS receptor (ipamorelin). The choice between them in a study is an experimental-design decision based on the receptor pathway under investigation, not a judgement of effectiveness for any applied or human outcome.
Frequently asked questions
No. CJC-1295 (without DAC) is a 29-amino-acid GHRH-receptor analogue; ipamorelin is a 5-amino-acid ghrelin / GHS-receptor ligand. Different receptors and sizes.
CJC-1295 acts on the GHRH receptor and is a Modified GRF (1-29) analogue; ipamorelin acts on the ghrelin / GHS receptor and is a pentapeptide.
Both are studied in growth-hormone-axis research and represent different receptor families (GHS vs GHRH). They are referenced together as research reference compounds, not as a human-use combination.
Both are available from PurePeptides at greater than 99% purity as lyophilised powders, with same-day dispatch before 3PM and tracked UK & EU delivery. They are sold strictly for laboratory research use only.
Research-grade Ipamorelin & CJC-1295 (without DAC)
Greater than 99% purity, lyophilised powder, same-day dispatch before 3PM with tracked UK & EU delivery. Research use only.
Buy Ipamorelin → Buy CJC-1295 (without DAC) →Disclaimer: All products supplied by PurePeptides are strictly for laboratory research use only. They are not for human or animal consumption and are not medical products. This comparison is informational and summarises publicly available research; it is not medical, clinical, or dosing advice.