For research purposes only. This comparison describes the chemical identity and research context of BPC-157 and TB-500. It is not medical advice, does not rank the compounds for any purpose, and does not describe any effect, dose, or use in humans or animals.
BPC-157 vs TB-500 at a glance
| Attribute | BPC-157 | TB-500 |
| Class | Synthetic pentadecapeptide | Synthetic Thymosin Beta-4 |
| Length | 15 aa | 43 aa |
| Approx. molecular weight | ~1419.6 g/mol | ~4963 g/mol |
| Receptor / target (research) | Tissue-repair research | Actin-binding / tissue repair |
| CAS number | 137525-51-0 | 77591-33-4 |
What is BPC-157?
BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide: a single chain of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV). It is a partial sequence derived from a protein identified in gastric juice, and is also referred to as PL 14736 or 'stable gastric pentadecapeptide'.
Read more in our BPC-157 research guide, or view the BPC-157 product page.
What is TB-500?
TB-500 is a synthetic peptide related to Thymosin Beta-4 (Tb4), a naturally occurring 43-amino-acid peptide. It is supplied as a lyophilised powder and used as a research-grade reference compound in laboratory work.
Read more in our TB-500 research guide, or view the TB-500 product page.
Key differences
Both are studied in tissue-repair research, but they are chemically unrelated. BPC-157 is a 15-amino-acid pentadecapeptide derived from a protein identified in gastric juice. TB-500 is a synthetic version of the 43-amino-acid actin-binding peptide Thymosin Beta-4. They differ in size, sequence and biological origin, and are associated with different molecular pathways in the literature — for example angiogenesis and connective-tissue biology for BPC-157, and actin regulation and cell migration for Thymosin Beta-4.
How researchers distinguish BPC-157 and TB-500
Researchers working in tissue-repair models may reference either or both as distinct experimental reference compounds. The choice reflects which biological pathway is under study, not a judgement of effectiveness for any applied or human outcome.
Frequently asked questions
No. BPC-157 is a 15-amino-acid pentadecapeptide from a gastric protein; TB-500 is a synthetic version of the 43-amino-acid Thymosin Beta-4. They are chemically unrelated.
Size, sequence and origin: BPC-157 (15 aa) derives from a gastric Body Protection Compound, while TB-500 (43 aa) is synthetic Thymosin Beta-4, an actin-binding peptide.
Both appear frequently in tissue-repair research literature, so they are often discussed together as distinct reference compounds in that field.
Both are available from PurePeptides at greater than 99% purity as lyophilised powders, with same-day dispatch before 3PM and tracked UK & EU delivery. They are sold strictly for laboratory research use only.
Research-grade BPC-157 & TB-500
Greater than 99% purity, lyophilised powder, same-day dispatch before 3PM with tracked UK & EU delivery. Research use only.
Buy BPC-157 → Buy TB-500 →Disclaimer: All products supplied by PurePeptides are strictly for laboratory research use only. They are not for human or animal consumption and are not medical products. This comparison is informational and summarises publicly available research; it is not medical, clinical, or dosing advice.