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BPC-157: Research Peptide Guide

What BPC-157 (Body Protection Compound 157) is, its chemical identity and sequence, how it is handled in laboratory research, and how it relates to other tissue-repair research peptides. For research use only.

For research purposes only. This guide describes the chemical identity and laboratory handling of BPC-157 and summarises findings reported in published research. It is not medical advice and does not describe any effect, dose, or use in humans or animals.

What is BPC-157?

BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide: a single chain of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV). It is a partial sequence derived from a protein identified in gastric juice, and is also referred to as PL 14736 or 'stable gastric pentadecapeptide'.

PurePeptides supplies BPC-157 as a lyophilised (freeze-dried) powder at greater than 99% purity, intended strictly as a research-grade reference compound for in-vitro laboratory use. The information on this page describes its chemical identity and laboratory handling only, and must not be interpreted as describing any effect in humans or animals.

BPC-157 is described in the literature as a “stable gastric pentadecapeptide” — a partial sequence of a Body Protection Compound originally identified in gastric juice. Its 15-residue chain (GEPPPGKPADDAGLV) is comparatively stable in aqueous solution, which is one reason it is so frequently used as a reference compound in preclinical tissue-repair and angiogenesis research.

Chemical identity & specifications

ProductBPC-157
Full nameBody Protection Compound 157
SynonymsPL 14736; stable gastric pentadecapeptide
ClassificationSynthetic pentadecapeptide
Amino-acid sequenceGEPPPGKPADDAGLV (15 aa)
Molecular weight~1419.55 g/mol
CAS number137525-51-0
SolubilityWater-soluble (bacteriostatic water)
Purity>99%
Physical formLyophilised powder
Storage-20°C lyophilised; 2-8°C reconstituted
Intended useResearch use only - not for human consumption

Handling BPC-157 in research protocols

In laboratory settings, lyophilised BPC-157 is typically stored at -20°C, protected from light and moisture, until use. For reconstitution, bacteriostatic water is a commonly cited solvent; once in solution, the material is generally kept refrigerated at 2-8°C with freeze-thaw cycles minimised to preserve peptide integrity.

Researchers quantify BPC-157 by concentration within their experimental system — for example molar concentrations for in-vitro work, or amount-per-mass figures in animal models. These are parameters defined by the study design and reported in the literature; they are not dosing guidance for any human or animal use. To convert between vial mass, solvent volume, and target concentration for laboratory preparation, our peptide reconstitution calculator may be useful.

Findings reported in the research literature

BPC-157 is among the most frequently cited peptides in preclinical tissue-repair research, appearing across in-vitro and animal-model studies of angiogenesis, cell migration and connective-tissue biology. It is typically referenced by its purity, sequence and stability when used as an experimental reference compound.

Any effects described in this literature are observations made in controlled experimental systems — cell assays and animal models — and are reported here only to summarise the scientific record. They do not constitute claims about outcomes, efficacy, benefits, or safety in humans, and nothing on this page should be read as encouraging human or animal use. Readers interested in the primary research can review the indexed literature via PubMed’s BPC-157 results.

BPC-157 and TB-500: tissue-repair research peptides

In the research-peptide literature, BPC-157 is frequently discussed alongside TB-500 (synthetic Thymosin Beta-4). Both are studied in models of cell migration, angiogenesis and tissue repair, but they are chemically distinct — different sequences, lengths and biological origins:

PeptideClassLengthApprox. MWOrigin
BPC-157Synthetic pentadecapeptide15 aa~1419.6 g/molPartial sequence from a gastric Body Protection Compound
TB-500Synthetic Thymosin Beta-443 aa~4963 g/molSynthetic version of naturally occurring Thymosin Beta-4

For the companion compound, see our TB-500 research guide. Both are supplied by PurePeptides strictly as research materials, with no claim regarding outcomes in humans or animals.

Purity and quality control in research-grade BPC-157

In laboratory research, peptide purity has a direct bearing on reproducibility: synthesis by-products or residual reagents can confound experimental observations. PurePeptides supplies BPC-157 at greater than 99% purity as a lyophilised powder.

In peptide manufacturing, purity is typically assessed by reverse-phase high-performance liquid chromatography (HPLC), while identity is confirmed by mass spectrometry (MS) against the expected molecular weight — approximately 1419.55 g/mol for BPC-157. A certificate of analysis (COA) documenting these results is available on request for the current batch. When evaluating any research-grade peptide, requesting the COA and confirming both the purity figure and the mass-spec identity is good laboratory practice.

Frequently asked questions

What is BPC-157?

BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid peptide with the sequence GEPPPGKPADDAGLV, supplied as a lyophilised powder for research use only.

What is the amino-acid sequence of BPC-157?

Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV), a chain of 15 amino acids.

What other names is BPC-157 known by?

It is also referred to as Body Protection Compound 157, PL 14736, and stable gastric pentadecapeptide.

How does BPC-157 differ from TB-500?

Both are studied in tissue-repair research, but they are chemically unrelated: BPC-157 is a 15-amino-acid pentadecapeptide derived from a gastric protein, whereas TB-500 is a synthetic version of the 43-amino-acid Thymosin Beta-4.

What purity is your BPC-157, and is a COA available?

PurePeptides supplies BPC-157 at greater than 99% purity as a lyophilised powder. A certificate of analysis (COA) is available on request for the current batch.

How should BPC-157 be stored and reconstituted?

Store the lyophilised powder at -20°C, protected from light and moisture. In the laboratory it is commonly reconstituted with bacteriostatic water; once in solution, store refrigerated at 2-8°C and minimise freeze-thaw cycles.

Where can I buy research-grade BPC-157?

Research-grade BPC-157 is available from PurePeptides at greater than 99% purity, with same-day dispatch before 3PM and tracked UK & EU delivery. It is sold strictly for laboratory research use only.

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Research-grade BPC-157

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Disclaimer: All products supplied by PurePeptides are strictly for laboratory research use only. They are not for human or animal consumption and are not medical products. This guide is informational and summarises publicly available research; it is not medical, clinical, or dosing advice.